Open Neuroscience Data

Over 200 TB of publicly available high-resolution brain imaging data hosted on the AWS Open NeuroData Registry.

Access

How to Access the Data

All datasets are freely available via AWS and RESTful APIs — no account required

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AWS S3 Registry

All data is hosted on the Open NeuroData Registry on AWS. Browse and download directly from S3.

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RESTful API

Query specific brain volumes programmatically using our cutout service. Example: GET /token/data/hdf5/4/512,1024/512,1024/512,1024/

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Web Viewer

Explore brain volumes interactively using the CATMAID web viewer — visualize, navigate and annotate 3D neuroanatomical data directly in your browser.

Datasets

Available Datasets

High-resolution neuroanatomical datasets from leading research groups worldwide

Amunts et al. 2015

BigBrain — ultra-high resolution 3D model of human brain at 20 μm resolution.

Human Brain · MRI
Bhatla et al. 2015

C. elegans connectome data — full wiring diagram of the nematode nervous system.

EM · Nematode
Bloss et al. 2016

Structured dendritic inhibition in mouse hippocampal CA1 pyramidal neurons.

EM · Hippocampus
Bloss et al. 2018

Single excitatory axons form clustered synapses onto CA1 pyramidal cell dendrites.

EM · Hippocampus
Bock et al. 2011

Network anatomy and in vivo physiology of visual cortical neurons — large-scale EM.

EM · Mouse Visual Cortex
Bumbarger et al. 2013

System-wide rewiring underlies behavioral differences in predatory and microbivorous nematodes.

EM · Nematode
Collman et al. 2015

Mapping synapses by conjugate light-electron array tomography — multi-channel data.

Array Tomography
Deisseroth et al. 2016

CLARITY technique datasets for structural and molecular interrogation of intact biological systems.

CLARITY
Dyer et al. 2016

Quantifying mesoscale neuroanatomy using X-ray microtomography.

X-ray Micro-CT
Harris et al. 2015

A dendritic spine survey of hippocampal CA3-CA1 synapses using serial section electron microscopy.

EM · Hippocampus
Hildebrand et al. 2017

Whole-brain serial-section electron microscopy in larval zebrafish.

EM · Zebrafish
Kasthuri et al. 2015

Saturated reconstruction of a volume of neocortex — 20 teravoxels of mouse visual cortex.

EM · Mouse Cortex
Lee et al. 2016

Anatomy and function of an excitatory network in the visual cortex.

EM · Visual Cortex
Micheva et al. 2015

A large fraction of neocortical synapses can be rapidly altered by motor learning.

Array Tomography
Ohyama et al. 2015

A multilevel multimodal circuit enhances action selection in Drosophila.

EM · Drosophila
Randlett et al. 2015

Whole-brain activity mapping onto a zebrafish brain atlas.

fMRI · Zebrafish
Takemura et al. 2013

A visual motion detection circuit suggested by Drosophila connectomics.

EM · Drosophila
Tobin et al. 2017

Cellular and circuit models of increased pheromone attraction after virgin experience.

EM · C. elegans
Wanner et al. 2016

Dense EM-based reconstruction of the interglomerular projectome in the zebrafish olfactory bulb.

EM · Zebrafish
Weiler et al. 2014

Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex.

Array Tomography